APR 2017

DAYSPA is the business resource for spa & wellness professionals! Each issue covers the latest in skin care, spa treatments, wellness services and management strategies.

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[ 54 ] • DAYSPA • april 2017 "Pluripotent cells can address more than one issue, whereas single-source cells can only infl uence the same cell types." HydroPeptide Soothing Serum TOP: © GETTY IMAGES Hyalogic Stem Cell Face Serum Ilike Organic Skin Care Grape Stem Cell Solutions Gel Mask M'lis Eye Serum the necessary information to stimulate skin stem cells without altering DNA. These factors also preserve the stem cells' multipotency (multiple differentiation) and ability to self- renew. The stem cells utilized in Pevonia products, for example, are derived from the Moroccan argan tree and Swiss comfrey root. Argan stem cells (not to be confused with argan oil) stimulate activity at the dermal level, increasing fi broblast production and improving connective tissue fi ber support. Comfrey root stem cells work at the base of the epidermis to stimulate cellular activity and restructure the epidermis. Nicoll: It's important to understand the difference between single-source cells and pluripotent cells. The advantage to pluripotent cells is that they can address more than one issue. Single-source cells can only infl uence the same cell types, therefore they're less effective in addressing various skin issues. Zone: There are two types of stem cells used in skin care. The fi rst are harvested from plants—typically from rare, ancient or unique species able to survive harsh habitats—that are then cultured. Examples include: apple, rose, argan or Dwarf soapwort, which protect stem cells in the skin and lessen the appearance of wrinkles; grape and soy stem cells, which deliver antioxidant benefi ts; and marine plant stem cells that can heal and lighten skin. The second kind is human stem cells, of which there are different types. The most controversial are embryonic stem cells, which are able to differentiate into all types of tissue in the human body. What are some key considerations when formulating with stem cells? Zone: Concentration is everything—the higher, the better. Stability and delivery are also concerns, which is why at DermAware we add bio-actives to stabilize and increase the longevity of our stem cells, and we also focus on microencapsulation to improve both delivery and stability. Dr. Jurist: In general, the most effective stem cell products rely on the extraction of epigenetic factors. Nevertheless, the challenge has been to maintain compatibility and sustained benefi ts. Obviously, human stem cells' epigenetic factor proteins are intrinsically more compatible in the skin, but non-human sources can also be benefi cial if selected and applied appropriately. As long as the ingredients have the molecular makeup necessary for interaction, then a response will be executed in the skin. Pevonia uses dual- action epigenetic factors from a combination of specifi c vegetal stem cells that are isolated, stabilized, encapsulated in liposomes and then delivered deep into target skin cells. Our formula also includes enzymes, peptides, growth factors and other components to maximize results. Asquith: Depending on the desired action of the product, various compensatory ingredients could be used. For example, if it's designed to be anti-infl ammatory, the stem cells can be combined with other soothing and protective ingredients. Most of today's stem cell products are formulated to address signs of aging, therefore hyaluronic acid, growth factors, Pevonia Stem Cells Phyto-Elite Intensive Body Corrector spotlight STEM CELL PRODUCTS

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